LYMPHOID NEOPLASIA Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type
نویسندگان
چکیده
1Inserm U955, Créteil, France; 2Faculté de Médecine, Université Paris 12, Créteil, France; 3Département de Pathologie, Assistance Publique–Hôpitaux de Paris (AP-HP), Groupe Henri-Mondor Albert-Chenevier, Créteil, France; 4Ligue Nationale Contre le Cancer, Paris, France; 5Pathology Department, Centre Hospitalo-Universitaire (CHU) Sart Tilman, University of Liège, Liège, Belgium; 6Inserm U976, Hôpital Saint-Louis, Paris, France; 7Department of Medical Biology and Pathology, Institut Gustave Roussy, Villejuif, France; 8Inserm U728 et Service de Pathologie, Hôpital Saint-Louis, Paris, France; 9Département de Pathologie, CHU Dupuytren, Limoges, France; 10Service d’Hématologie et de Thérapie Cellulaire, Hôpital Saint-Antoine and Université Pierre et Marie Curie, Paris, France; 11The Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, United Kingdom; 12Service de pathologie, Hôpital Ambroise Paré, AP-HP et EA4340, Université de Versailles, Saint-Quentin-en-Yvelines, France; and 13Laboratoire d’Immunologie Biologique, AP-HP, Groupe Henri-Mondor Albert-Chenevier, Créteil, France
منابع مشابه
Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type.
Biopsies and cell lines of natural killer/T-cell lymphoma, nasal type (NKTCL) were subject to combined gene expression profiling and array-based comparative genomic hybridization analyses. Compared with peripheral T-cell lymphoma, not otherwise specified, NKTCL had greater transcript levels for NK-cell and cytotoxic molecules, especially granzyme H. Compared with normal NKcells, tumors were clo...
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